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This review summarizes recent discoveries that add to the list of known moonlighting proteins. They include several different kinds of proteins and combinations of functions.

Aug 1, 2003 · A single protein with multiple functions might seem surprising, but there are actually many cases of proteins that 'moonlight', or have more than one role in an organism.

Oct 11, 2023 · A single protein with multiple functions might seem surprising, but there are actually many cases of proteins that ‘moonlight’, or have more than one role in an organism.

Therefore, this review describes certain basic aspects of moonlighting functions and their mechanism of action, surface layer proteins and their moonlighting functions of commensal bacteria and their transition towards biomimetics.

Moonlighting proteins are expressed throughout the evolutionary tree and function in many different biochemical pathways. Some moonlighting proteins can perform both functions...

This database provides a centralized, web-based location to organize information about moonlighting proteins for which there is biochemical and/or biophysical evidence of both functions being performed by the same protein.

The known examples of moonlighting proteins include diverse types of proteins, including receptors, enzymes, transcription factors, adhesins and scaffolds, and different combinations of functions are observed.

A single protein with multiple functions might seem surprising, but there are actually many cases of proteins that ‘moonlight’, or have more than one role in an organism.

Jan 1, 1999 · The idea of one gene—one protein—one function has become too simple because increasing numbers of proteins are found to have two or more different functions. The multiple functions of such moonlighting proteins add another dimension to cellular complexity and benefit cells in several ways.

Jan 1, 2024 · The purpose of the present review is to describe the diverse moonlighting functions ascribed to the main metabolic pathways in different kingdoms of life. We discuss the implications and new functions of proteins with regard to controlling metabolism in …

This article discusses examples of moonlighting proteins, how one protein structure can perform two diferent functions, and how the multiple functions can be regulated.

Mar 22, 2017 · Studies of the structures and functions of moonlighting proteins like these can help elucidate how proteins switch activities in response to changes within or surrounding the cell, whether it’s due to changes in pH, substrate availability, cellular …

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